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Estrogen is the predominant sex hormone that slows bone loss, even in men. Adolescents also seek hormone therapy for treatment of gender dysphoria. Some people find injections to be painful. Martin den Heijer , professor of endocrinology 1 2 , Alex Bakker , transgender man with 20 years of experience taking hormonal treatment , Louis Gooren , emeritus professor in transgender medicine 2 1 Department of internal medicine, VU Medical Center, Amsterdam, Netherlands 2 Center of expertise on gender dysphoria, VU Medical Center, Amsterdam, Netherlands Correspondence to M den Heijer m. The American Journal of Physiology. Sex steroids—testosterone and estradiol—are necessary to maintain bone health in men and women, respectively. Bone mass, bone geometry, and body composition in female-to-male transsexual persons after long-term cross-sex hormonal therapy. Sex steroid antagonists via disinhibition of the HPG axis:
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I catch that sort of thing easily. The milk ducts give rise to milk glands that also begin to grow. There is further enlargement and elevation of the breast and areola with no separation of their contours.
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